More than 43,500 people across six countries have taken part in the trial, which has been hailed as a scientific breakthrough in the fight against the pandemic.
The trial is double blind meaning participants have no idea if they have been injected with a placebo or with the vaccine – but some who reported suffering side-effects believe they were given the real dose.
Glenn Deshields, 44, Austin, Texas, is confident he did not receive a placebo after suffering with side-effects that he likened to a hangover.
The lobbyist, who said he was ‘very excited’ by the trial data, said he later received an antibody test through his doctor which came back positive.
He added: ‘My grandfather, one of his first memories was of the bells ringing when World War I ended.
‘It was a horrific war and horrible things happened and people were just happy it was over with.
‘In my mind I felt the same way… I kind of felt it was something like that. Thank god, it’s going to be over at some point.’
Volunteer Carrie, 45, from Missouri, received her first shot back in September and a her second last month.
She said she suffered with a headache, fever and aches over her body after her first shot, which became more severe after the second.
Carrie, who works in publishing, felt signing up for the trial was a ‘civic duty’ and said Monday’s positive news left her feeling ‘very proud’.
She said: ‘There are so many people who have had it and suffered.
‘The thought that we could do something to stop people from suffering from this, from losing family members, that we could get rid of it and get back to some sort of normal in our lives – that’s a driving factor for this for me.